THE NEED
Adhesions are a major surgical complication without solution
Almost 100% occurrence in open surgical procedures
Severe strain on health systems
Complications include:
•Small bowel obstruction (SBO)
•Chronic pain
•Secondary infertility
•Difficulties in repeat surgeries
Patient anxiety and discomfort
Require re-operation
Multi billion dollar problem
SURGICAL ADHESIONS – A HUGE UNMET NEED
Surgical adhesions are a major source of healthcare expenditure:
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34% of people who have underwent an abdominal surgery will end up in the hospital within 5 years due to disorders and surgical complications related to adhesions 1
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2.3B USD in direct inpatient expenses in the US 2
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Major indications in the US (CDC): 6M abdominal surgeries; 1.25M C-sections; 600K Hysterectomies every year
1. Lancet. 2020 Jan 4;395(10217):33-41
2. BMC Surg. 2011; 11: 13
3 Lancet. 1999 May 1;353(9163):1476-80
4 Rev Obstet Gynecol. 2009;2(1):38-45
Every 3rd open surgery requires
re-surgeries 3
Every 5th open surgery leads to chronic pain 3
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Every 5th case of female infertility 4
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Every 4th gynecological laparoscopy 4